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Symbol
Name
ID

Polb
polymerase (DNA directed), beta
MGI:97740

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Hepatosplenomegaly
Disease(s) Associated with POLB	Hepatosplenomegaly
pancreatic cancer

Mouse Phenotypes		increased splenocyte apoptosis	abnormal immunoglobulin heavy chain V(D)J recombination	abnormal somatic hypermutation frequency	increased mean platelet volume	increased germinal center B cell number	increased T-helper 2 cell number	abnormal spleen germinal center morphology	increased spleen germinal center number	increased IgG level
Availability	Mouse Genotype	increased splenocyte apoptosis	abnormal immunoglobulin heavy chain V(D)J recombination	abnormal somatic hypermutation frequency	increased mean platelet volume	increased germinal center B cell number	increased T-helper 2 cell number	abnormal spleen germinal center morphology	increased spleen germinal center number	increased IgG level
	Polb^tm1.1Jbsw/Polb^tm1.1Jbsw
	Polb^tm1.1Jbsw/Polb⁺
	Polb^{tm1a(KOMP)Wtsi}/Polb⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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